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Fulham did not emerge from their cup triumph over Norwich unscathed, as defender Calvin Bassey suffered a recurrence of a previous back injury, although Silva did not offer an update on the ex-Ajax man in his pre-game press conference.
Tosin Adarabioyo (groin) and Adama Traore (thigh) are also confined to the medical bay, while Kenny Tete will need a once-over due to a groin issue of his own, but Sasa Lukic has now returned to team training following his knee concern.
In what will mark his 200th career league appearance, Andreas Pereira will be one of several players rested in midweek to return to the XI - a list which also includes Bernd Leno, Tim Ream, Antonee Robinson and Harrison Reed.
Fulham possible starting lineup:
Leno; Tete, Diop, Ream, Robinson; Palhinha, Reed; Decordova-Reid, Pereira, Iwobi; Jimenez
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Chelsea also lost a defender to injury in their recent EFL Cup showdown, and Pochettino has offered a pessimistic update on Ben Chilwell's hamstring injury, which will consign the left-back to the infirmary for an unspecified period of time.
The Blues doctors are already working overtime to treat Romeo Lavia (ankle), Benoit Badiashile (hamstring), Reece James (hamstring), Christopher Nkunku (knee), Wesley Fofana (knee), Marcus Bettinelli (knee) and Trevoh Chalobah (hamstring), but Pochettino is hopeful that Carney Chukwuemeka and Noni Madueke might be able to be involved in some capacity.
On the naughty step are Jackson and Malo Gusto - the latter's absence should see Marc Cucurella take up right-back duties again, while Raheem Sterling may operate as a makeshift striker in Jackson's absence if Armando Broja is not deemed ready for a start just yet after his devastating knee injury.
Chelsea
possible starting lineup:
Sanchez; Cucurella, Disasi, Silva, Colwill; Caicedo, Fernandez, Gallagher; Palmer, Sterling, Mudryk
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