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Fulham winger Willian, formerly of Arsenal, remains doubtful with a thigh injury, while Adama Traore and Tim Ream both remain sidelined with respective thigh and calf problems.
However, Raul Jimenez has served his three-match suspension and is expected to replace Rodrigo Muniz up front, joining Bobby De-Cordova Reid and Alex Iwobi, another ex-Gunner, in attack.
Silva is unlikely to make too many other changes to his starting lineup, although Harrison Reed could be recalled at the expense of Tom Cairney to start alongside in-demand midfielder Palhinha.
Fulham possible starting lineup:
Leno; Tete, Adarabioyo, Bassey, Robinson; Palhinha, Reed; Decordova-Reid, Pereira, Iwobi; Jimenez
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For Arsenal, Takehiro Tomiyasu (calf), Thomas Partey (thigh), Fabio Vieira (groin), Jurrien Timber (knee) all remain sidelined as they continue to recover from injury.
However, Kai Havertz is available to return after serving a one-game suspension in midweek and the German will be pushing to start in midfield alongside Declan Rice and Martin Odegaard.
The potential inclusion of Havertz could see either Leandro Trossard or Gabriel Martinelli drop down to the substitutes' bench, and the other handed a start on the left side of attack alongside Gabriel Jesus and Bukayo Saka, the latter of whom scored against Fulham in the reverse fixture.
Arsenal possible starting lineup:
Raya; White, Saliba, Gabriel, Zinchenko; Odegaard, Rice, Havertz; Saka, Jesus, Trossard
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