Fulham will welcome Burnley to Craven Cottage on Monday evening knowing that a defeat to the Clarets would see them relegated back to the Championship for the 2021-22 campaign.
Scott Parker's side are currently 18th in the Premier League table, nine points behind 17th-placed Burnley, with both sides having four games of the 2020-21 season left to play.
A mini-revival earlier this year aided suggestions that Fulham could escape the bottom three, but the Cottagers have now lost five of their last six Premier League matches, including a 2-0 loss at Chelsea last time out, picking up just a single point during that run.
As a result, the Cottagers are 18th in the table, nine points behind 17th-placed Burnley, meaning that a defeat for the home side on Monday evening would confirm their relegation back to the second tier.
At one stage, Newcastle United appeared to be the side that Fulham could catch, but the Magpies are now 13th in the table, helped by their impressive 4-2 win over Leicester City on Friday evening.
Fulham have simply not won enough matches this season, picking up maximum points in just five of their 34 Premier League matches, and they are now only one point ahead of 19th-placed West Bromwich Albion.
Parker's team will be targeting wins in their next four matches against Burnley, Southampton, Manchester United and Newcastle, but it does appear that the club are heading back to the Championship.
Burnley, meanwhile, will enter Monday's clash off the back of a 2-1 home defeat to West Ham United, with Michail Antonio scoring a brace for the Champions League-chasing Hammers.
Sean Dyche's side recorded a 4-0 win away to Wolverhampton Wanderers on April 25, but they have actually lost four of their last five in the league, which has seen them slide down into 17th spot in the table.
The Clarets have avoided defeat in eight of their 17 away league fixtures this term and will be taking on a Fulham side with the worst home record in the 2020-21 Premier League season.
A defeat for Burnley on Monday would certainly leave them looking over their shoulder, though, particularly ahead of two tough fixtures against Leeds United and Liverpool, before finishing the season away to already-relegated Sheffield United.
Dyche's team have already won at Craven Cottage this term, recording a 3-0 victory in the FA Cup back in January, but the points were shared in a 1-1 draw in the reverse league fixture at Turf Moor in February.
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Fulham have won eight of their past nine home league matches against Burnley.
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Burnley have won just one of the five Premier League meetings, losing on both their visits to Craven Cottage.
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However, the Clarets beat Fulham 3-0 at Craven Cottage in the FA Cup earlier this season - the last time Burnley won two away games against the same side in a season was at the expense of Blackpool in 1992-93.
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Fulham have only managed one point from their past six games.
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A 12th home league defeat of the season would be a club record.
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They have scored just nine goals in their 17 home league matches this season, including only three in their last 11. No English top-flight team has ever failed to reach double figures for home goals in a season.
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The Cottagers are unbeaten in all nine league fixtures this season against the other teams who began this matchround in the bottom seven of the table.
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Burnley have won just three of their past 15 league matches, with all of them coming in away fixtures.
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The Clarets have scored 12 goals in six away league games, as many as in their previous 18.
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They have only won one of their 10 Premier League fixtures this campaign against the other teams who began this matchround in the bottom seven of the table.
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Sean Dyche's side have not received a red card in 89 Premier League matches since Robbie Brady was sent off at Huddersfield in January 2019. Only Ipswich Town (94, 1992-1994) have had a longer run of Premier League fixtures without a red card.