Fulham's Premier League game at Tottenham on Wednesday is in doubt after the southwest London club returned a number of positive COVID-19 tests.
Fulham are now in talks with the Premier League, whose board must approve any match postponement.
It comes as the league returned its highest number of positive COVID-19 tests this season.
Fulham manager Scott Parker had said there were no issues with the squad's fitness at his news conference earlier today, but this was held before the latest COVID-19 test results came through.
Parker revealed in his press conference on Tuesday he had tested negative on Sunday to ensure he was able to return to the training ground at the start of this week after a period of self-isolation.
The 40-year-old missed the goalless draw with Southampton on Boxing Day after a member of his household tested positive for coronavirus.
The Premier League is yet to comment on the Fulham and Spurs fixture, although it released a statement regarding the positive tests, confirming that on "Monday 21 December and Sunday 27 December, 1,479 players and club staff were tested for COVID-19.
"Of these, there were 18 new positive tests. Players or club staff who have tested positive will self-isolate for a period of 10 days.
"The Premier League is providing this aggregated information for the purposes of competition integrity and transparency," it added.
"No specific details as to clubs or individuals will be provided by the league and results will be made public after each round of testing."