Fulham will edge further away from the drop zone if they avoid defeat to Bournemouth on home turf.
Kit Symons's men are currently eight points above the bottom three, though they head into the game at the Cottage on the back of a narrow 1-0 defeat to Watford - their fourth loss in six.
Goals from Brett Pitman and Harry Arter ensured that Bournemouth beat Fulham 2-0 when the sides met at Dean Court back in December.
Lasse Vigen Christensen remains sidelined for the hosts with a hamstring injury, while Scott Parker could be in line for a recall after missing the game with Watford due to a knee problem.
Bournemouth could enter the automatic promotion places in the Championship table on Friday night with a win over Fulham at Craven Cottage.
The Cherries ended a run of five league games without a win on Tuesday as they earned a 2-1 victory against Wolverhampton Wanderers.
Eddie Howe's side were given a further boost in their bid to finish in the top two with Derby County's 2-0 defeat to Brighton & Hove Albion.
Bournemouth have no fresh injury concerns ahead of their trip to the capital, but Howe is likely to make changes after seeing his team play just four days previously.
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Bournemouth won the earlier meeting this season 2-0 at the Goldsands Stadium on Boxing Day.
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Bournemouth are unbeaten in the last five meetings, winning three. Fulham's last win was 3-1 away in the old Division Two in January 1994.
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Bournemouth are unbeaten in the last four meetings at Craven Cottage, winning two. Fulham's last win at home was 2-0 in the old Division Three in April 1992.
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Fulham have won only one of their last 10 games in all competitions. Their only win since mid-January was 2-0 against Derby at home in the Championship on Saturday.
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Fulham have lost only one of their last five home games in the Championship. Their only league defeat at Craven Cottage in 2015 was 2-1 against Ipswich on 14 February.
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Fulham have conceded in 70% of their last 20 home games.
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Fulham have scored first in 60% of their last 20 home games.
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Fulham have kept a clean sheet in 30% of their last 20 home games.
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Bournemouth won 2-1 against Wolves at home on Tuesday - their first win in six games.
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Bournemouth have won only one of their last five away games in all competitions. Their only win on the road since mid-January was 3-1 at Wigan in the Championship on 7 February.
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Bournemouth have conceded in 70% of their last 20 away games.
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Bournemouth have scored first in 50% of their last 20 away games.
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Bournemouth have kept a clean sheet in 30% of their last 20 away games.