With Rangers sitting bottom of the Premier League and without a win all season, the board have decided to terminate the former Manchester City manager's contract.
QPR have sacked Mark Hughes after a run of 12 games without a win this season has left the club bottom of the Premier League.
Defeat at home to relegation rivals Southampton last weekend seemed to be the final straw with some fans holding banners which called for the appointment of former Tottenham boss, Harry Redknapp.
The club released a statement on their website explaining the decision to remove the Welshman from his duties as manager.
"This decision has been taken after careful consideration by the Board of Directors, following numerous meetings over the last few days.
"The Board of Directors wish to thank Mark for his commitment, hard work and dedication in his ten months in charge.
"Mark has shown integrity and professionalism throughout his time here, but ultimately the circumstances we find ourselves in have left the Board of Directors with very little choice but to make a change.
"The Board will now be working actively to put a new managerial structure in place as soon as possible.
"Mark Bowen and Eddie Niedzwiecki will take charge of the R's trip to Manchester United in the Barclays Premier League on Saturday afternoon."