Bolton Wanderers Ivan Klasnic's 66th-minute winner set up a FA Cup fifth round clash with Fulham after Wanderers saw off Wigan at the second attempt.
The Croatian striker rifled in the replay's only goal in a game Owen Coyle's side dominated at the DW Stadium.
Bolton will now face Mark Hughes' team at Craven Cottage on Sunday at 15.00 with a place in the quarter-finals up for grabs.